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Hemophilia Treatment: Advancements and Approaches
Hemophilia is a rare genetic disorder that impairs the blood’s ability to clot, leading to prolonged bleeding after injuries or even spontaneous bleeding episodes. This condition arises due to a deficiency or absence of clotting factors—proteins essential for blood coagulation. Hemophilia primarily affects males, though females can be carriers, and it is categorized into two main types: Hemophilia A (factor VIII deficiency) and Hemophilia B (factor IX deficiency). Effective treatment is crucial to prevent severe complications, such as joint damage, internal bleeding, and life-threatening hemorrhages.
Conventional Treatment Approaches
The cornerstone of hemophilia treatment is replacement therapy, where the missing clotting factors are administered to the patient through intravenous infusion. These clotting factors can be derived from donated human plasma or produced synthetically using recombinant DNA technology. Prophylactic infusions, given regularly even in the absence of bleeding, have become standard practice for severe hemophilia, significantly reducing…
